Michael G Caparon Selected Research

NAD+ Nucleosidase (NAD(P) Nucleosidase)

2/2016	The NADase-Negative Variant of the Streptococcus pyogenes Toxin NAD⁺ Glycohydrolase Induces JNK1-Mediated Programmed Cellular Necrosis.
9/2015	The Streptococcus pyogenes NAD(+) glycohydrolase modulates epithelial cell PARylation and HMGB1 release.
9/2015	Dual modes of membrane binding direct pore formation by Streptolysin O.
11/2014	A novel cholesterol-insensitive mode of membrane binding promotes cytolysin-mediated translocation by Streptolysin O.
7/2010	Variation in Streptococcus pyogenes NAD+ glycohydrolase is associated with tissue tropism.

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Michael G Caparon Research Topics

Disease

26	Infections 01/2022 - 01/2005
12	Urinary Tract Infections (Urinary Tract Infection) 09/2020 - 10/2010
7	Inflammation (Inflammations) 01/2019 - 01/2013
3	Endocarditis 08/2016 - 10/2013
3	Foreign Bodies (Foreign Body) 01/2013 - 10/2010
2	Bacteriuria 09/2020 - 09/2012
2	Necrosis 02/2016 - 09/2015
2	Soft Tissue Infections 04/2015 - 07/2009
1	Cross Infection (Nosocomial Infection) 01/2022
1	Sepsis (Septicemia) 10/2019
1	Meningitis 10/2019
1	Bacterial Infections (Bacterial Infection) 04/2015
1	Disease Progression 12/2013
1	Persistent Infection 10/2010
1	Starvation 07/2009
1	Myositis (Idiopathic Inflammatory Myopathies) 01/2004

Drug/Important Bio-Agent (IBA)

5	Virulence Factors (Pathogenicity Factors)IBA 10/2019 - 09/2005
5	NAD+ Nucleosidase (NAD(P) Nucleosidase)IBA 02/2016 - 07/2010
3	Anti-Bacterial Agents (Antibiotics)IBA 01/2022 - 09/2012
3	Cysteine Proteases (Cysteine Protease)IBA 01/2017 - 09/2005
3	Fibrinogen (Factor I)FDA Link 10/2016 - 09/2014
2	CytokinesIBA 01/2022 - 10/2010
2	PerforinIBA 09/2015 - 11/2014
2	CholesterolIBA 09/2015 - 11/2014
2	streptolysin OIBA 09/2015 - 11/2014
2	CitrullineIBA 04/2015 - 01/2014
2	Arginine (L-Arginine)FDA Link 04/2015 - 01/2014
2	Fimbriae Proteins (Pilin)IBA 10/2013 - 01/2012
2	Proteins (Proteins, Gene)FDA Link 10/2013 - 07/2009
1	LipidsIBA 01/2022
1	Interleukin-1 (Interleukin 1)IBA 01/2022
1	Glutathione (Reduced Glutathione)IBA 10/2019
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019
1	Peptide Hydrolases (Proteases)FDA Link 01/2017
1	Immune Sera (Antisera)IBA 10/2016
1	Glycoside Hydrolases (Endoglycosidases)IBA 02/2016
1	Reactive Oxygen Species (Oxygen Radicals)IBA 02/2016
1	NAD (NADH)IBA 02/2016
1	Interleukin-17 (Interleukin 17)IBA 01/2016
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2016
1	Interleukin-8 (Interleukin 8)IBA 09/2015
1	HMGB1 Protein (HMG1)IBA 09/2015
1	AcidsIBA 04/2015
1	malic acid (malate)IBA 03/2015
1	VaccinesIBA 09/2014
1	AntibodiesIBA 09/2014
1	Estradiol (Delestrogen)FDA LinkGeneric 05/2013
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2013
1	Biological ProductsIBA 09/2012
1	MannosidesIBA 09/2012
1	MetalsIBA 01/2012
1	CarbohydratesIBA 02/2011
1	InterleukinsIBA 10/2010
1	Macrophage Inflammatory Proteins (Macrophage Inflammatory Protein 1)IBA 10/2010
1	streptolysin SIBA 11/2009
1	ZincIBA 07/2009
1	Streptokinase FDA Link 09/2005
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2005
1	Glutathione PeroxidaseIBA 01/2004

Therapy/Procedure

11	Catheters 09/2020 - 10/2010
2	Therapeutics 10/2016 - 09/2012
2	Urinary Catheters 10/2016 - 09/2012
1	Indwelling Catheters (Indwelling Catheter) 10/2010